Sr Research Investigator

Bristol-Myers Squibb Redwood City, CA

About the Job

Description:

Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. And driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Bristol-Myers Squibb (BMS) Department of Metabolism and Pharmacokinetics seeks a scientist who wants to be a successful drug hunter in the areas of oncology biologics discovery (e.g., cancer immunotherapeutics, antibody drug conjugates, etc.).  The selected individual is expected to represent the Department on drug discovery working groups and early clinical development teams in the area of pharmacokinetics (PK)/pharmacodynamics (PD) to improve drug candidate designs, define differentiation strategies, and apply modeling and simulations to facilitate translational PK/PD efforts.  The individual is also expected to take mechanistic approaches to better understand drug disposition profiles and target pharmacology, a foundation that is crucial to our success in predicting human pharmacokinetics and efficacious dose of novel drug candidates and modalities.  At BMS, we take pride in applying model-based approaches for the quantitative integration of PK/PD/efficacy/toxicity data in order to broadly impact on drug discovery and development processes.  A sound understanding of PK and PD principles and hands-on experience in modeling and simulation are critical to this role.  Ultimately, the selected candidate is expected to provide scientifically sound approaches and data for effective decision-making and enable advancement of drug candidates into clinical development.

Qualification:

• A Ph.D. in pharmacokinetics or other related discipline, with 3- to 5-year industrial experience, is required. 

• A sound understanding of pharmacokinetic and pharmacodynamic principles and demonstrated problem-solving skills are essential to this job. 

• Hands-on modeling experience is a requirement. 

• In addition, strong communication skills and ability to work and collaborate in a multi-discipline team setting are required for this function.