Program Leader Late Stage Oncology Biomarker
Bristol-Myers Squibb Princeton, NJ
About the Job
Program Leader Late Stage Biomarker
Bristol-Myers Squibb is actively conducting translational medicine research to further our understanding of cancer biology and to identify which patient populations may be more likely to derive benefit from Immuno-Oncology (I-O). Bristol-Myers Squibb has long believed the future of cancer research is dependent on investments in science and partnerships. Collaboration is integrated into our organizational framework across translational medicine and R&D.
The Program Leader is responsible for developing and executing on translational strategies for the Oncology/hematology pipeline. This scientist works on various projects across all stages of drug development and will act as a key interface with the Translational Medicine group.
The successful candidate will be responsible for integrating translational research and clinical development, developing a biomarker strategy in alignment with clinical development objectives, leading efforts for data generation, interpretation and communication to the development teams. The candidate will also be responsible for understanding the external research environment, partnering with discovery biology and other functions both internally and with external partners to coordinate the execution of deliverables.
- Manages a group of 8-10 clinical biomarkers and focuses on the delivery of the biomarker strategy for tumor areas such as lung, GI, Heme, and Melanoma & GU.
- Proactively develops talent across the organization and leverages external network to connect others with hiring needs.
- Creates opportunities for others within and outside of own team to develop new skills and experiences (both Biomarker related & otherwise).
- Participates in the Biomarker & Diagnostic Leadership team to set the global biomarker and diagnostic strategy for BMS.
- Builds and maintains networks within and outside of the organization to both strengthen their understanding of the big picture and leverage diverse perspectives, experiences and expertise to maximize performance.
- Independently engages with development teams and technical/scientific experts to define, revise and progress biomarker plans.
- Effectively engages with teams and governance bodies and utilizes advisory bodies to define, revise and progress biomarker plans
- Delivers high quality biomarker strategies for target engagement, pharmacodynamic endpoints and patient selection (where appropriate).
- Proactively provides insight into novel ways to incorporate biomarkers into clinical designs to enable early understanding of emerging drug profiles.
- Effectively interfaces with the Translational Medicine group to obtain appropriate resources to deliver on biomarker goals.
- Collaborates and strategizes across the entire Oncology organization to improve efficiency and accelerate the product pipeline forward.
- As appropriate, provides biomarker expertise to progress validated biomarkers into development of pharmacodiagnostic tools.
This position reports to the Head of Oncology Biomarkers and is based in Lawrenceville, New JerseyQualification:
- MD or PhD, or equivalent advanced biology degree
- Experienced scientist with 9+ years’ experience in the drug development process.
- Deep understanding of the role of translational research/medicine and clinical biomarkers in drug development
- Excellent communication skills across all levels within an organization and external.
- Experienced manager of people and projects including demonstrated ability to grow new leaders and delegate key projects appropriately.
- Demonstrated ability to lead others through change by navigating ambiguity, creating the context, and engaging individuals.
- Comfortable working in a fast-paced environment where speed is paramount
- Willing to work as a topic expert, outside of a traditional functional environment, in a team unified around serving the assets
- Ability to recognize, articulate, and accept calculated risks to make informed decisions
- Willingness and ability to effectively cooperate and partner with external providers and others within BMS
- Demonstrated experience in the appropriate application of various scientific technologies into translational research strategies
- Working knowledge of all functional areas of drug development, including, biology, toxicology, clinical development, diagnostic development, etc.
- Demonstrated scientific acumen and mechanistic understanding of disease biology